Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits peptide disulfide oxidoreductase activity. Involved in cell redox homeostasis; negative regulation of protein export from nucleus; and negative regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleus. Is expressed in central nervous system; skeleton; and submandibular gland primordium. Orthologous to human TXN (thioredoxin).