Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits ankyrin binding activity. Involved in several processes, including chordate embryonic development; forward locomotion; and heart development. Localizes to M band and Z disc. Is expressed in several structures, including diaphragm; embryo mesenchyme; heart; musculature; and tarsus. Used to study autosomal recessive limb-girdle muscular dystrophy type 2J; dilated cardiomyopathy 1G; and tibial muscular dystrophy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin).