Automated description from the Alliance of Genome Resources
Exhibits thyroid-stimulating hormone receptor activity. Involved in several processes, including inner ear development; positive regulation of cold-induced thermogenesis; and positive regulation of growth. Localizes to the plasma membrane. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in Graves' disease; cardiomyopathy; congenital nongoitrous hypothyroidism 1; and mitral valve prolapse. Is expressed in bladder; renal vasculature; thyroid gland; and thyroid gland lobe. Orthologous to human TSHR (thyroid stimulating hormone receptor).