Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits thyroid-stimulating hormone receptor activity. Involved in several processes, including dopaminergic neuron differentiation; inner ear development; and positive regulation of cold-induced thermogenesis. Localizes to plasma membrane. Is expressed in bladder; renal vasculature; thyroid gland; and thyroid gland lobe. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in Graves' disease; cardiomyopathy; congenital nongoitrous hypothyroidism 1; and mitral valve prolapse. Orthologous to human TSHR (thyroid stimulating hormone receptor).