Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables chromatin binding activity; histone H3K9 demethylase activity; and transcription coregulator activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of transcription by RNA polymerase II; and spermatid nucleus elongation. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including cerebral cortex; extraembryonic ectoderm; and pituitary gland. Used to study obesity. Human ortholog(s) of this gene implicated in cervical cancer and colon cancer. Orthologous to human KDM3A (lysine demethylase 3A).