Automated description from the Alliance of Genome Resources
Exhibits tryptophan 5-monooxygenase activity. Involved in bone remodeling; mammary gland alveolus development; and positive regulation of fat cell differentiation. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; borderline personality disorder; mental depression (multiple); and scoliosis. Orthologous to human TPH1 (tryptophan hydroxylase 1).