Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity. Involved in several processes, including DNA conformation change; embryonic cleavage; and female meiotic nuclear division. Localizes to condensed chromosome and nucleolus. Predicted to colocalize with centriole and nuclear chromosome. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human TOP2A (DNA topoisomerase II alpha).