Automated description from the Alliance of Genome Resources
Exhibits chromatin DNA binding activity and nuclear receptor activity. Involved in several processes, including female mating behavior; generation of neurons; and regulation of transcription by RNA polymerase II. Localizes to the nucleus. Colocalizes with the nuclear chromatin. Used to study attention deficit hyperactivity disorder; thyroid gland follicular carcinoma; and thyroid hormone resistance syndrome. Human ortholog(s) of this gene implicated in breast cancer (multiple); cervix uteri carcinoma in situ; prostate cancer; renal cell carcinoma; and thyroid hormone resistance syndrome. Is expressed in several structures, including brown fat; endocrine gland; liver; sensory organ; and vestibulo-cochlear ganglion. Orthologous to human THRB (thyroid hormone receptor beta).