Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits extracellular matrix binding activity. Involved in several processes, including cellular response to nitric oxide; circulatory system development; and monocyte aggregation. Localizes to extracellular space and sarcoplasmic reticulum. Is expressed in several structures, including brain; limb; respiratory system; sensory organ; and skeleton. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in cholangiocarcinoma; pancreatic cancer; and pancreatic ductal carcinoma. Orthologous to human THBS1 (thrombospondin 1).