Automated description from the Alliance of Genome Resources
Exhibits extracellular matrix binding activity. Involved in several processes, including cellular response to nitric oxide; circulatory system development; and positive regulation of macrophage chemotaxis. Localizes to the extracellular space and sarcoplasmic reticulum. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in cholangiocarcinoma; pancreatic cancer; and pancreatic ductal carcinoma. Orthologous to human THBS1 (thrombospondin 1).