Automated description from the Alliance of Genome Resources (Release 4.0)
Exhibits identical protein binding activity. Involved in iodide transport; regulation of myelination; and thyroid hormone generation. Localizes to extracellular space. Is expressed in thyroid gland; thyroid gland follicle; thyroid gland left lobe colloid-filled follicles; thyroid gland lobe; and thyroid gland right lobe colloid-filled follicles. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in Graves' disease; autoimmune thyroiditis; goiter; and thyroid dyshormonogenesis 3. Orthologous to human TG (thyroglobulin).