Automated description from the Alliance of Genome Resources
Exhibits protein tyrosine kinase activity and signaling receptor activity. Involved in several processes, including circulatory system development; negative regulation of endothelial cell apoptotic process; and positive regulation of protein transport. Localizes to the perinuclear region of cytoplasm. Predicted to colocalize with the actin filament and stress fiber. Human ortholog(s) of this gene implicated in arteriovenous malformation and multiple cutaneous and mucosal venous malformations. Is expressed in several structures, including cardiovascular system; central nervous system; extraembryonic component; genitourinary system; and hemolymphoid system gland. Orthologous to human TEK (TEK receptor tyrosine kinase).