Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits protein tyrosine kinase activity and signaling receptor activity. Involved in several processes, including circulatory system development; negative regulation of endothelial cell apoptotic process; and positive regulation of protein transport. Localizes to perinuclear region of cytoplasm. Predicted to colocalize with actin filament and stress fiber. Is expressed in several structures, including cardiovascular system; central nervous system; extraembryonic component; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in arteriovenous malformation and multiple cutaneous and mucosal venous malformations. Orthologous to human TEK (TEK receptor tyrosine kinase).