Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Sry. (This text reflects annotations as of Tuesday, July 8, 2014.)

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Summary text based on GO annotations supported by experimental evidence in mouse

• Researchers have inferred from direct assay, that the gene product of Sry
  • participates in the following biological processes:
    • male gonad development ^[]
    • negative regulation of gene expression ^[]
    • regulation of transcription from RNA polymerase II promoter ^[]
    • transcription from RNA polymerase II promoter ^[]
  • performs the following molecular functions:
    • DNA binding ^[]
    • DNA binding, bending ^[]
    • protein heterodimerization activity ^[]
    • sequence-specific DNA binding RNA polymerase II transcription factor activity ^[]
  • is located in the following cellular components:
    • nuclear transcription factor complex ^[]
    • nucleus ^{[, , ]}
• Researchers have inferred, based on genetic interactions, that the gene product of Sry
  • participates in the following biological processes:
    • male sex determination based on interactions with Fgf9, Nr0b1, Sox9 ^{[, ]}
    • negative regulation of transcription from RNA polymerase II promoter based on interactions with Sry ^[]
    • sex determination based on interactions with Nr0b1 ^[]

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Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe Sry indicates that it:
  • participates in the following biological processes:
    • cell differentiation
    • regulation of transcription, DNA-templated
    • sex differentiation
    • transcription, DNA-templated
  • performs the following molecular functions:
    • calmodulin binding
  • is located in the following cellular components:
    • cytoplasm

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References

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Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

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