Automated description from the Alliance of Genome Resources (Release 3.1)
Exhibits several functions, including DNA-binding transcription factor activity; identical protein binding activity; and protein heterodimerization activity. Contributes to DNA-binding transcription activator activity, RNA polymerase II-specific and E-box binding activity. Involved in several processes, including histone acetylation; immune system development; and positive regulation of nitrogen compound metabolic process. Localizes to RNA polymerase II transcription regulator complex and nuclear nucleosome. Is expressed in several structures, including branchial arch; central nervous system; male reproductive system; retina; and urinary system. Human ortholog(s) of this gene implicated in agammaglobulinemia and colorectal cancer. Orthologous to human TCF3 (transcription factor 3).