Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits ATPase-coupled peptide antigen transmembrane transporter activity and MHC class I protein binding activity. Predicted to contribute to peptide antigen binding activity and peptide transmembrane transporter activity. Involved in defense response. Localizes to mitochondrion. Is expressed in cranium; early conceptus; limb; nervous system; and oocyte. Human ortholog(s) of this gene implicated in several diseases, including MHC class I deficiency; autoimmune disease (multiple); bronchial disease (multiple); diffuse scleroderma; and lung disease (multiple). Orthologous to human TAP1 (transporter 1, ATP binding cassette subfamily B member).