Automated description from the Alliance of Genome Resources
Exhibits ATPase-coupled peptide antigen transmembrane transporter activity and MHC class I protein binding activity. Predicted to contribute to peptide antigen binding activity and peptide transmembrane transporter activity. Involved in defense response. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including MHC class I deficiency; bone inflammation disease (multiple); bronchial disease (multiple); diffuse scleroderma; and lung disease (multiple). Orthologous to human TAP1 (transporter 1, ATP binding cassette subfamily B member).