Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits Ras guanyl-nucleotide exchange factor activity. Involved in several processes, including animal organ development; regulation of T cell activation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to several cellular components, including neuronal cell body; plasma membrane; and postsynaptic density. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and retina. Used to study Noonan syndrome 4. Human ortholog(s) of this gene implicated in Noonan syndrome; Noonan syndrome 4; and gingival fibromatosis. Orthologous to human SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1).