Automated description from the Alliance of Genome Resources
Exhibits superoxide dismutase activity. Involved in several processes, including animal organ development; apoptotic signaling pathway; and regulation of cellular biosynthetic process. Localizes to the mitochondrion. Used to study Canavan disease; Leigh disease; amyotrophic lateral sclerosis type 1; congestive heart failure; and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetes mellitus (multiple); endocrine gland cancer (multiple); lipid storage disease (multiple); and optic nerve disease (multiple). Orthologous to human SOD2 (superoxide dismutase 2).