Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables epidermal growth factor binding activity; identical protein binding activity; and signaling receptor binding activity. Involved in insulin-like growth factor receptor signaling pathway. Acts upstream of or within several processes, including circulatory system development; epidermal growth factor receptor signaling pathway; and positive regulation of MAPK cascade. Predicted to be located in endosome membrane. Predicted to be part of Shc-EGFR complex. Predicted to be active in plasma membrane. Is expressed in several structures, including cerebral cortex; early conceptus; liver; skeleton; and skin. Orthologous to human SHC1 (SHC adaptor protein 1).