Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of cytokine production; protein autoubiquitination; and regulation of pattern recognition receptor signaling pathway. Acts upstream of or within response to bacterium. Located in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; heart; and limb. Orthologous to human TRIM5 (tripartite motif containing 5).