Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable beta-carotene 15,15'-dioxygenase activity; carboxylic ester hydrolase activity; and retinol isomerase activity. Predicted to be involved in several processes, including detection of light stimulus involved in visual perception; retina homeostasis; and terpenoid metabolic process. Predicted to act upstream of or within lipid metabolic process and visual perception. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in eye and urinary system. Used to study Leber congenital amaurosis 2 and retinitis pigmentosa 20. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 2; retinitis pigmentosa; retinitis pigmentosa 20; and retinitis pigmentosa 87. Orthologous to human RPE65 (retinoid isomerohydrolase RPE65).