Automated description from the Alliance of Genome Resources
Exhibits retinal isomerase activity. Involved in several processes, including cellular response to electrical stimulus; regulation of rhodopsin gene expression; and retinal metabolic process. Predicted to localize to the cell body and endoplasmic reticulum membrane. Used to study Leber congenital amaurosis 2 and retinitis pigmentosa 20. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 2; retinitis pigmentosa; and retinitis pigmentosa 20. Orthologous to human RPE65 (retinoid isomerohydrolase RPE65).