Automated description from the Alliance of Genome Resources
Exhibits endopeptidase activity. Involved in several processes, including animal organ development; drinking behavior; and regulation of systemic arterial blood pressure by renin-angiotensin. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy; hypertension; and portal hypertension. Orthologous to human REN (renin).