Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits endopeptidase activity. Involved in several processes, including drinking behavior; male gonad development; and regulation of systemic arterial blood pressure by renin-angiotensin. Localizes to extracellular space and intracellular. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; hindbrain; and trunk. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy; hypertension; and portal hypertension. Orthologous to human REN (renin).