Automated description from the Alliance of Genome Resources (Release 8.1.0)
Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen and peroxidase activity. Involved in cyclooxygenase pathway and long-chain fatty acid biosynthetic process. Acts upstream of or within prostaglandin biosynthetic process; regulation of blood pressure; and regulation of cell population proliferation. Located in cytoplasm and photoreceptor outer segment. Is active in endoplasmic reticulum lumen. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and sensory organ. Used to study pre-eclampsia. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human PTGS1 (prostaglandin-endoperoxide synthase 1).
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