Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable FAD binding activity; amino acid binding activity; and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate and regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. Predicted to act upstream of or within proline metabolic process. Located in mitochondrion. Is expressed in several structures, including adipose tissue; cardiovascular system; central nervous system; forelimb bud; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in amino acid metabolic disorder; hyperprolinemia type 1; and schizophrenia 4. Orthologous to human PRODH (proline dehydrogenase 1).