Automated description from the Alliance of Genome Resources
Exhibits pyruvate kinase activity. Involved in response to other organism. Localizes to the cytoplasm and plasma membrane. Used to study malaria and pyruvate kinase deficiency of red cells. Human ortholog(s) of this gene implicated in Gaucher's disease; congenital nonspherocytic hemolytic anemia; malaria; pyruvate kinase deficiency of red cells; and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PKLR (pyruvate kinase L/R).