Automated description from the Alliance of Genome Resources
Predicted to have ATPase-coupled intramembrane lipid transporter activity and ATPase-coupled transmembrane transporter activity. Involved in bile acid secretion and response to fenofibrate. Localizes to the intercellular canaliculus and plasma membrane. Used to study cholecystitis; cholestasis; hepatocellular carcinoma; intrahepatic cholestasis; and primary sclerosing cholangitis. Human ortholog(s) of this gene implicated in cholestasis (multiple); gallbladder disease; and liver cirrhosis (multiple). Is expressed in alimentary system and liver. Orthologous to human ABCB4 (ATP binding cassette subfamily B member 4).