Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have ATPase-coupled transmembrane transporter activity and phosphatidylcholine floppase activity. Involved in bile acid secretion and response to fenofibrate. Localizes to intercellular canaliculus and plasma membrane. Is expressed in alimentary system and liver. Used to study cholecystitis; cholestasis; hepatocellular carcinoma; intrahepatic cholestasis; and primary sclerosing cholangitis. Human ortholog(s) of this gene implicated in cholestasis (multiple); gallbladder disease; and liver cirrhosis (multiple). Orthologous to human ABCB4 (ATP binding cassette subfamily B member 4).