Automated description from the Alliance of Genome Resources
Predicted to have ATPase-coupled intramembrane lipid transporter activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in several processes, including Sertoli cell barrier remodeling; establishment of endothelial blood-brain barrier; and response to drug. Localizes to the intercellular canaliculus. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; allergic rhinitis; carcinoma (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Is expressed in several structures, including central nervous system; early conceptus; oocyte; and small intestine. Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1).