Automated description from the Alliance of Genome Resources (Release 4.0)
Enables 6-phosphofructokinase activity. Acts upstream of or within several processes, including fructose 6-phosphate metabolic process; glycolytic process through fructose-6-phosphate; and negative regulation of insulin secretion. Located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human PFKL (phosphofructokinase, liver type).