Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable neuropeptide hormone activity and opioid receptor binding activity. Predicted to be involved in chemical synaptic transmission; neuropeptide signaling pathway; and sensory perception. Predicted to act upstream of or within signal transduction. Predicted to be located in several cellular components, including Golgi apparatus; dendritic spine; and dense core granule. Predicted to be active in several cellular components, including hippocampal mossy fiber to CA3 synapse; neuronal cell body; and secretory vesicle. Is expressed in several structures, including central nervous system; oviduct; and retina. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; amphetamine abuse; drug dependence (multiple); and spinocerebellar ataxia type 23. Orthologous to human PDYN (prodynorphin).