Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables platelet-derived growth factor alpha-receptor activity and platelet-derived growth factor binding activity. Involved in several processes, including animal organ development; platelet-derived growth factor receptor-alpha signaling pathway; and protein phosphorylation. Acts upstream of or within several processes, including animal organ development; face morphogenesis; and signal transduction involved in regulation of gene expression. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and microvillus. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and heart and pericardium. Used to study congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in hematologic cancer (multiple); hypereosinophilic syndrome; and pancreatic cancer. Orthologous to human PDGFRA (platelet derived growth factor receptor alpha).