Automated description from the Alliance of Genome Resources
Exhibits transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; positive regulation of nitrogen compound metabolic process; and regulation of kidney development. Localizes to the nucleus. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in congenital hypothyroidism and congenital nongoitrous hypothyroidism 2. Is expressed in several structures, including central nervous system; embryo ectoderm; foregut gland; genitourinary system; and spleen. Orthologous to human PAX8 (paired box 8).