Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled opioid receptor activity. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; adult locomotory behavior; and neuropeptide signaling pathway. Located in membrane. Is active in neuronal dense core vesicle. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and neural retina. Human ortholog(s) of this gene implicated in heroin dependence and opiate dependence. Orthologous to human OPRD1 (opioid receptor delta 1).