Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Oprd1. (This text reflects annotations as of Tuesday, July 8, 2014.)

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Summary text based on GO annotations supported by experimental evidence in mouse

• Researchers have inferred from direct assay, that the gene product of Oprd1
  • participates in the following biological processes:
    • adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ^[]
    • neuropeptide signaling pathway ^[]
  • performs the following molecular functions:
    • opioid receptor activity ^{[, ]}
  • is located in the following cellular components:
    • integral component of membrane ^[]
    • membrane ^[]
• Researchers have inferred, based on phenotypic analysis of mouse mutants, that the gene product of Oprd1
  • participates in the following biological processes:
    • adult locomotory behavior ^[]
    • opioid receptor signaling pathway ^[]
  • performs the following molecular functions:
    • opioid receptor activity ^[]

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Summary text based on GO annotations supported by experimental evidence in other organisms

• From comparative sequence analysis (see table for details), MGI curators have determined that the gene product of Oprd1:
  • participates in the following biological processes:
    • G-protein coupled receptor signaling pathway
    • opioid receptor signaling pathway
    • phospholipase C-activating G-protein coupled receptor signaling pathway
    • protein import into nucleus, translocation
    • regulation of calcium ion transport
    • regulation of sensory perception of pain
  • performs the following molecular functions:
    • enkephalin receptor activity
    • opioid receptor activity
  • is located in the following cellular components:
    • axon terminus
    • cytoplasm
    • dendrite membrane
    • intrinsic component of plasma membrane
    • membrane raft
    • plasma membrane
    • postsynaptic membrane
    • vesicle

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Summary text based on GO annotations supported by structural data

• Oprd1 encodes a protein or proteins that contain the following InterPro domains: indicating that the gene product:
  • performs the following molecular functions:
    • G-protein coupled receptor activity

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Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe Oprd1 indicates that it:
  • participates in the following biological processes:
    • signal transduction
  • performs the following molecular functions:
    • G-protein coupled receptor activity
    • signal transducer activity

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References

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Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

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