Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables guanylate cyclase activity. Involved in regulation of blood pressure. Acts upstream of or within cGMP biosynthetic process. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and respiratory system. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human NPR1 (natriuretic peptide receptor 1).