Automated description from the Alliance of Genome Resources (Release 5.3.0)
Predicted to enable hormone receptor binding activity; neuropeptide hormone activity; and neuropeptide receptor binding activity. Involved in female pregnancy and regulation of blood pressure. Acts upstream of or within cardiac muscle hypertrophy in response to stress; negative regulation of blood pressure; and sodium ion export across plasma membrane. Located in cytoplasm and extracellular space. Is expressed in several structures, including heart. Used to study hypertension. Human ortholog(s) of this gene implicated in artery disease (multiple); congestive heart failure; heart conduction disease (multiple); and peritonitis. Orthologous to human NPPA (natriuretic peptide A).