Automated description from the Alliance of Genome Resources
Exhibits nitric-oxide synthase activity. Involved in several processes, including negative regulation of ion transport; nitric oxide biosynthetic process; and positive regulation of nitrogen compound metabolic process. Localizes to several cellular components, including the T-tubule; calyx of Held; and cytoplasm. Colocalizes with the caveola. Used to study achalasia and hypertrophic pyloric stenosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; asthma; cystic fibrosis; and hypertrophic pyloric stenosis. Orthologous to human NOS1 (nitric oxide synthase 1).