Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits nitric-oxide synthase activity. Involved in several processes, including nitric oxide biosynthetic process; positive regulation of nitrogen compound metabolic process; and regulation of ion transport. Localizes to several cellular components, including T-tubule; Z disc; and calyx of Held. Colocalizes with caveola. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study achalasia and hypertrophic pyloric stenosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; asthma; cystic fibrosis; and hypertrophic pyloric stenosis. Orthologous to human NOS1 (nitric oxide synthase 1).