Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits several functions, including DNA-binding transcription factor activity; MADS box domain binding activity; and sequence-specific DNA binding activity. Involved in several processes, including animal organ development; chordate embryonic development; and regulation of transcription, DNA-templated. Localizes to nucleus. Used to study prostate cancer. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is expressed in several structures, including arterial system; central nervous system; reproductive system; tooth; and urinary system. Orthologous to human NKX3-1 (NK3 homeobox 1).