Automated description from the Alliance of Genome Resources
Exhibits Rab GTPase binding activity; death receptor activity; and nerve growth factor binding activity. Involved in several processes, including circadian regulation of gene expression; nervous system development; and regulation of signal transduction. Localizes to several cellular components, including the cell surface; cell-cell junction; and postsynaptic density. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human NGFR (nerve growth factor receptor).