Automated description from the Alliance of Genome Resources
Exhibits transmembrane receptor protein tyrosine kinase activator activity. Involved in several processes, including cell surface receptor signaling pathway; nervous system development; and positive regulation of macromolecule metabolic process. Localizes to the neuron projection terminus. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; end stage renal failure; hereditary sensory and autonomic neuropathy type 5; interstitial cystitis; and neurogenic bladder. Orthologous to human NGF (nerve growth factor).