Automated description from the Alliance of Genome Resources
Predicted to have hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides and serine-type endopeptidase activity. Involved in positive regulation of phosphatidylinositol 3-kinase activity and small GTPase mediated signal transduction. Predicted to localize to the extracellular space; protein-containing complex; and secretory granule. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal failure; hypertension; and myocardial infarction. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to several human genes including KLK1 (kallikrein 1).