Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides and serine-type endopeptidase activity. Acts upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction and small GTPase-mediated signal transduction. Predicted to be located in several cellular components, including acrosomal vesicle; apical part of cell; and extracellular space. Predicted to be part of protein-containing complex. Predicted to be active in secretory granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1).