Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have beta-catenin binding activity; integrin binding activity; and protein domain specific binding activity. Involved in several processes, including animal organ development; ectoderm development; and negative regulation of protein phosphorylation. Localizes to several cellular components, including adherens junction; cleavage furrow; and ruffle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study familial meningioma; neurofibromatosis; otitis media; and renal cell carcinoma. Human ortholog(s) of this gene implicated in familial meningioma; neurilemmomatosis; and neurofibromatosis 2. Orthologous to human NF2 (neurofibromin 2).