Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits GTPase activator activity. Involved in several processes, including animal organ development; modulation of chemical synaptic transmission; and nervous system development. Localizes to cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and integumental system. Used to study juvenile myelomonocytic leukemia and neurofibromatosis. Human ortholog(s) of this gene implicated in autistic disorder; central nervous system cancer (multiple); hematologic cancer (multiple); neurofibromatosis 1; and neurofibromatosis-Noonan syndrome. Orthologous to human NF1 (neurofibromin 1).