Automated description from the Alliance of Genome Resources
Exhibits GTPase activator activity. Involved in several processes, including animal organ development; modulation of chemical synaptic transmission; and nervous system development. Localizes to the cytoplasm. Used to study juvenile myelomonocytic leukemia and neurofibromatosis. Human ortholog(s) of this gene implicated in acute myeloid leukemia; autistic disorder; juvenile myelomonocytic leukemia; malignant glioma; and optic nerve glioma. Orthologous to human NF1 (neurofibromin 1).