Automated description from the Alliance of Genome Resources
Exhibits 14-3-3 protein binding activity. Involved in several processes, including growth; regulation of DNA damage checkpoint; and response to ionizing radiation. Localizes to the centrosome and nucleus. Used to study autosomal recessive polycystic kidney disease. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; asphyxiating thoracic dystrophy; and short-rib thoracic dysplasia 6 with or without polydactyly. Is expressed in several structures, including central nervous system; ganglia; gonad; lung; and spleen. Orthologous to human NEK1 (NIMA related kinase 1).