Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits Rac GTPase binding activity. Contributes to superoxide-generating NAD(P)H oxidase activity. Involved in superoxide anion generation. Localizes to acrosomal vesicle. Is expressed in several structures, including hemolymphoid system; limb; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal recessive chronic granulomatous disease cytochrome b-positive type II. Orthologous to human NCF2 (neutrophil cytosolic factor 2).