Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and chromatin binding activity. Contributes to DNA binding activity. Involved in several processes, including cellular response to estradiol stimulus; positive regulation of snRNA transcription by RNA polymerase II; and skeletal muscle cell differentiation. Acts upstream of or within several processes, including myotube differentiation; regulation of RNA metabolic process; and skeletal muscle fiber adaptation. Located in myofibril and nucleus. Part of euchromatin and transcription regulator complex. Is expressed in several structures, including alimentary system; embryo mesenchyme; limb; limb bud; and skeletal musculature. Human ortholog(s) of this gene implicated in congenital myopathy 17. Orthologous to human MYOD1 (myogenic differentiation 1).