Automated description from the Alliance of Genome Resources (Release 4.1.0)
Predicted to enable several functions, including core promoter sequence-specific DNA binding activity; metal ion binding activity; and metalloendopeptidase activity. Involved in several processes, including protein import into nucleus; regulation of gene expression; and regulation of type I interferon-mediated signaling pathway. Acts upstream of or within bronchiole development and lung alveolus development. Located in extracellular space and nucleus. Is expressed in gonad; mesonephros; and testis. Human ortholog(s) of this gene implicated in Barrett's esophagus; artery disease (multiple); coronary aneurysm; esophagus adenocarcinoma; and multiple sclerosis. Orthologous to human MMP12 (matrix metallopeptidase 12).