Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits peptidase activity. Involved in several processes, including amyloid-beta clearance; amyloid-beta metabolic process; and positive regulation of long-term synaptic potentiation. Localizes to several cellular components, including dendrite; neuron projection terminus; and synaptic vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver and biliary system; and mammary gland. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2T; cerebellar ataxia type 43; cerebral amyloid angiopathy; and membranous glomerulonephritis. Orthologous to human MME (membrane metalloendopeptidase).