Automated description from the Alliance of Genome Resources
Exhibits peptidase activity. Involved in several processes, including amyloid-beta clearance; amyloid-beta metabolic process; and positive regulation of long-term synaptic potentiation. Localizes to the membrane; neuron projection; and synaptic vesicle. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2T; cerebral amyloid angiopathy; hereditary ataxia; and membranous glomerulonephritis. Orthologous to human MME (membrane metalloendopeptidase).