Automated description from the Alliance of Genome Resources
Exhibits methyltransferase activity. Involved in DNA dealkylation involved in DNA repair and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to localize to the nucleoplasm. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); malignant glioma (multiple); retinoblastoma; and urinary bladder cancer. Orthologous to human MGMT (O-6-methylguanine-DNA methyltransferase).