Automated description from the Alliance of Genome Resources
Exhibits protein-lysine 6-oxidase activity. Involved in several processes, including circulatory system development; collagen fibril organization; and regulation of signal transduction. Localizes to the collagen trimer and extracellular matrix. Used to study Menkes disease and Williams-Beuren syndrome. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome; Menkes disease; hypertension; and thoracic aortic aneurysm. Is expressed in several structures, including alimentary system; genitourinary system; heart and pericardium; lung; and sensory organ. Orthologous to human LOX (lysyl oxidase).