Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.2.0)

Enables phospholipase binding activity and sequence-specific double-stranded DNA binding activity. A structural constituent of nuclear lamina. Predicted to be involved in several processes, including cellular response to L-glutamate; nucleus organization; and protein localization to nuclear envelope. Located in nuclear inner membrane and nuclear lumen. Is active in nuclear lamina. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and musculoskeletal system. Used to study typical adult-onset autosomal dominant demyelinating leukodystrophy. Human ortholog(s) of this gene implicated in atypical autosomal dominant adult-onset demyelinating leukodystrophy; autosomal dominant primary microcephaly 26; and typical adult-onset autosomal dominant demyelinating leukodystrophy. Orthologous to human LMNB1 (lamin B1).

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Gene Ontology Evidence Code Abbreviations:

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