Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have carbohydrate binding activity and protein heterodimerization activity. Involved in establishment of skin barrier and negative regulation of inflammatory response. Localizes to keratin filament. Is expressed in autopod; nose; skin; and tongue. Used to study epidermolytic hyperkeratosis. Human ortholog(s) of this gene implicated in epidermolytic hyperkeratosis; epidermolytic palmoplantar keratoderma; and nonepidermolytic palmoplantar keratoderma. Orthologous to human KRT1 (keratin 1).