Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have scaffold protein binding activity. Involved in extrinsic apoptotic signaling pathway; hepatocyte apoptotic process; and tumor necrosis factor-mediated signaling pathway. Localizes to cell periphery and keratin filament. Human ortholog(s) of this gene implicated in liver cirrhosis. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Orthologous to human KRT18 (keratin 18).