Automated description from the Alliance of Genome Resources (Release 4.2.0)
Enables potassium channel inhibitor activity and voltage-gated potassium channel activity. Acts upstream of or within several processes, including negative regulation of potassium ion transport; potassium ion transport; and regulation of vasoconstriction. Located in intercalated disc and plasma membrane. Is expressed in several structures, including gut; heart; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in familial atrial fibrillation and pulmonary hypertension. Orthologous to human KCNA5 (potassium voltage-gated channel subfamily A member 5).