Automated description from the Alliance of Genome Resources
Exhibits potassium channel inhibitor activity and voltage-gated potassium channel activity. Involved in several processes, including Notch signaling pathway; negative regulation of potassium ion transport; and regulation of vasoconstriction. Localizes to the intercalated disc and plasma membrane. Human ortholog(s) of this gene implicated in familial atrial fibrillation and pulmonary hypertension. Is expressed in several structures, including gut; heart; metanephros; nervous system; and sensory organ. Orthologous to human KCNA5 (potassium voltage-gated channel subfamily A member 5).