Automated description from the Alliance of Genome Resources
Exhibits inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity and phosphatidylinositol binding activity. Involved in several processes, including calcium ion transport into cytosol; long-term synaptic potentiation; and sensory perception of taste. Localizes to the cytoplasm; endoplasmic reticulum membrane; and nuclear lumen. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is expressed in jaw; sensory organ; and skeleton. Orthologous to human ITPR3 (inositol 1,4,5-trisphosphate receptor type 3).